The immune system is one of the hardest working systems in the body. It is constantly working in the background, searching the body for bacterias and any potentially harmful pathogens. The first attacker in the line of defense is secretory IGA (SIgA). SIgA is the predominant immunoglobulin that is produced in the lining of the gut. Some functions of SIgA include trapping mucus, neutralizing enzymes and other toxins, inhibiting the adherence of pathogens, having interaction with antimicrobial factors like lactoferrin, all while being tolerant of the friendly flora. Any type of infection will lower SIgA. It is important to note that other factors that reduce SIgA include stress, a poor diet containing low levels of nutrients, genetics, the integrity of your gut lining, and age.Â
