– If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us. Thank You…
Dr Alex Jimenez & ( Talent) Discuss topics and issues …
Our genes have been linked to playing a role in inflammation. Polymorphisms have been noted in several genes to result in higher proinflammatory markers.It is important to remember that nutrition and lifestyle interventions can affect these genes and how they are expressed. For every one pound an individual is overweight, it puts ten pounds on your joints. This is an early life stressor that easily leads to chronic low-grade inflammation. Additionally, this can lead to diabetes, depression, cancers, and even cardiovascular diseases. We use DNA Health from DNA Life to determine an individual’s genetic predisposition and risk factors when it comes to inflammation
The detoxification process has two separate phases, both equally important. In phase one, our body requires “activator†enzymes. These enzymes hold the responsibility of activating a substance that needs to be removed. Once this process is complete, we move on to phase two detoxification. During phase two, we use “excretor†enzymes. These enzymes catalyze reactions that lead to the excretion of the toxins from the body. The way this process works is by binding the “active†toxins from phase one with glutathione in order to make the compounds water-soluble. Water-soluble compounds have the ability to be excreted through sweat or urine. With specific gene variants or deletions within this process, individuals have an increased risk for inflammation, cancers, and other health conditions.
DNA methylation is a very important factor in our biochemical pathways. Methylation uses a process of donating methyl groups to a substrate. These methyl group substrates contain DNA and RNA, chemicals, neurotransmitters, hormones, and immune cells. A few examples of methylation include: regulating gene expression, biotransformation, myelination which is the production of the protective coating that surrounds our nerves), building neurotransmitters, immune cells, processing hormones, and DNA/RNA synthesis.
Taste perception impacts the food choices we make, our nutrition, and our overall health. Genetically speaking, the taste response we have represents a phenotype. The five taste qualities we have include sweet, bitter, salty, umami, and sour. Genetics shows that humans who are more susceptible to the liking of sugar and fat are influenced by a specific genotype. Similar to this, individuals who have the ability to detect bitterness and rotting food have another genotype. Understanding the genotype people possess is highly important and can be used to create tailored programs for individuals.
Exercise has been proven to help many medical conditions and reduce inflammation. However, those who are high risk do not usually feel comfortable exercising. Treating disease and developing a program for long-term health is the overall goal with exercise prescriptions. To begin, all patients must undergo an assessment of physical capabilities as well as physiological. The hard push of exercise is not something all patients are mentally ready to tolerate.
The first Polycystic Ovary Syndrome (PCOS) conference was held in 1990 and discussed what PCOS is and how they were diagnosing and treating patients. They looked at oligo-anovulation, no ovulation, and too many androgens. Now, we use the Rotterdam criteria. This criterion groups together anovulation abnormal ovulation, clinical hirsutism acne (signs of hyperandrogens), and an ultrasound to view the presence of 12 or more follicles and determines if you have two out of those three then you are diagnosed with PCOS. There are multiple pathways that PCOS develops. Ultimately, these pathways are categorized into 4 groups: LIfestyle induced PCOS, Poor Fat Digestion/Sugar Burner, Inflammatory Diet/Poor Food Choices, and Genetic Predisposition.
For those who have lactose intolerance, the LCT gene transcription is reduced, leading to a low level of lactase. To turn off LCT it involves blocking an activator or turning up a repressor. In fact, it is theorized that lactase persistence is a human evolutionary adaptation to drinking milk from domesticated animals. The mutation in the gene started to appear around the same time as the domestication of cattle.
Depression is a natural response of the body and brain when there are biochemical imbalances occurring. These imbalances can involve toxicities, inflammation, metabolic issues, and genetic predispositions. When we are in a stressful state that lasts for too long, dysautonomia occurs and we burn out, leading to depression. Bun out is what occurs when any system is operating at too high of levels for too long. No matter what the issue is, depression or adrenal exhaustion, all chronic health issues can be related back to stress. We have the ability to test the neurotransmitters and take on depression from a holistic approach.
Our genetics are heavily influenced by the environment. This meaning that the way and times our genes express heavily depend on the micronutrients and toxins we surround our bodies with. Research has found that by eating a diet specific to your genes, you have the potential to alter when the genes express, reducing your overall risk of disease. We use diagnostic laboratory testing to assess your genetic makeup and create a personalized plan for you. By discovering what diseases you are more susceptible to, genetic testing allows us to create a path that will lead you to optimal health in the future.
The mitochondria is the “powerhouse of the cellâ€. It obtained this nickname by being the creator of ATP, or the energy our body produces to carry out functions. However, the mitochondria is responsible for so much more than that. More recently, studies have been showing a link between mitochondrial health and degenerative age-related diseases such as type 2 diabetes, Alzheimer’s, and others. Mitochondrial dysfunction can be linked and grouped into three categories: neurodegenerative diseases, immune diseases, and hepatic diseases.
Every single cell in our body requires energy to complete its functions. The energy our body creates and uses is known as ATP. ATP is created in the mitochondria and relies on a mixture of proteins, fats, and carbohydrates to source its fuel. This energy is created in an essential process called The Krebs Cycle. Similar to other functions throughout the body, when inflammation occurs important process can become hindered and not performed to their greatest extent. We have the ability to maximize our Krebs Cycle by the food we eat, ultimately leading to a postive alteration in our genes and reduced inflammation throughout our body.
As humans, we share genetic similarities and differences. Our genes are associated with our cellular defense and the risk we have for diseases. Additionally, part of our genetic differences include the rate in which enzymes in our bodies operate. Enzymes are important when it comes to cellular health as they determine the speed and activity of genes. Our diet heavily impacts our genetic expression and the metabolic pathways involved in all cellular functions. In order to reduce muscle pain, improve skeletal and overall health, diet needs to be considered as one of the top forms of medicine.
As humans we need ATP to sustain life. ATP is the energy our bodies use to perform cellular functions. To properly create ATP we need a combination of fats, carbohydrates, and proteins (macronutrients). To take these substances and convert them into ATP, our body uses a metabolic pathway referred to as the Citric Acid Cycle. The Citric Acid Cycle is what supplies the body with its primary energy. Without proper energy production from the Citric Acid Cycle we feel fatigued, muscle pain, and our body may suffer from inflammation. Organic acids are a result obtained from metabolic pathways such as the Citric Acid Cycle. We have the ability to assess your body’s energy production by measuring Organic Acids with diagnostic lab testing.
A neurotransmitter is a chemical messenger that regulates physical processes. Neurotransmitters are responsible for movement, pain, stress, emotions, cognition, energy, cravings, and more. Neurotransmitters imbalances are not only found in the brain but they are excreted outside of the Central Nervous System as well. Neurotransmitters play a role in influencing our digestion, nutrient absorption and impact our musculoskeletal system. When neurotransmitters are off-balance, individuals experience headaches, mood swings, anxiety, fatigue, pain, and depression. Using diagnostic lab technology, we have the ability to test our patients for neurotransmitter deficiencies.
Genes are highly essential and many are still unstudied. We are constantly uncovering more information about our genetic makeup and the factors that influence them. Now, we understand that food and dietary components play a large role in specific gene expressions and the environment around us is responsible for certain genetic expression as well! We have affordable ways to get your genes tested and can provide you with more insight on your genetic makeup.