All disease starts in the gut, but how? Intestinal permeability is a great contributor to metabolic and chronic conditions, as it allows bacterial translocation. Furthermore,…
It was first isolated from the Bovine Pineal gland in 1958. Nevertheless, in humans, it is the main hormone secreted by the pineal gland. Melatonin…
The overweight and obesity epidemic has taken over the world, promoting the prevalence of chronic diseases. The common denominator of this problem is our sedentary…
The nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) is a multimeric protein that recognizes different PAMPs and DAMPs. Furthermore,…
Inflammation is a necessary response, and it can initiate host defense response and repair damaged tissue. However, an uncontrolled inflammatory signal can cause prolonged inflammatory…
Tight Junctions (TJ) comprise different proteins that bind to the actin cytoskeleton to provide barrier integrity to our gut lining. Indeed, TJs are key assistance…
Our main interaction with food, pathogens, and inflammatory signals is made through our intestinal barrier. Indeed, our gut epithelium is where the absorption, digestion, transportation…
At the current moment, we are still struggling with the COVID-19 pandemic. Even today, we are bombarded with medical information on how to prevent complications…