The detoxification process has two separate phases, both equally important. In phase one, our body requires â€œactivatorâ€ enzymes. These enzymes hold the responsibility of activating a substance that needs to be removed. Once this process is complete, we move on to phase two detoxification. During phase two, we use â€œexcretorâ€ enzymes. These enzymes catalyze reactions that lead to the excretion of the toxins from the body. The way this process works is by binding the â€œactiveâ€ toxins from phase one with glutathione in order to make the compounds water-soluble. Water-soluble compounds have the ability to be excreted through sweat or urine. With specific gene variants or deletions within this process, individuals have an increased risk for inflammation, cancers, and other health conditions.