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TheÂ gut system’s primary functionÂ is to make sure that the consumed food that a person eats is digested in the stomach, and the intestines (both large and small) and is absorbed into nutrients for the entire body to stay functional. TheÂ gut microbiotaÂ makes sure that the body’s energy, growth, metabolism, and immune support are doing their jobs correctly and that the bacteria in the gut are thriving. When harmful bacteria start to disrupt the balance in the intestines, it can cause many chronicÂ gut disordersÂ in the gut system. However, incorporating probiotics into a healthy diet can help alleviate the symptoms by dampening their effects on the gut. In this 2 part series, we will be looking at how probiotics can help dampen the impact of gut disorders.Â Part 1Â looked at what probiotics are and how they alter the gut microbiome. By referring patients to qualified and skilled providers who specialize in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only.Â Disclaimer
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How Probiotics Help The Gut Microbiota
The gut microbiota makes sure that the entire body is functioning properly by regulating the body’s growth, metabolism, and immune support. When probiotics enter the gut system, they provide a protective barrier to preventÂ intestinal permeabilityÂ from getting disrupted.Â Research studies have foundÂ that intestinal microbes can convert dietary nutrients into metabolites. When probiotics are introduced into the gut microbiota and can help restore the composition of the gut. When there are factors that can affect the probiotic function, they are often defined as subjects that are “permissive” or “resistant” to probiotic strains based on:
- Pre-Supplementation Commensal Microbiota: Species in low abundance in a given region were more permissive to similar probiotic strains.
- Host immune System Function
- Digestive Functions
- Xenobiotic Metabolic Pathways
Other research studies have foundÂ that probiotics are live microorganisms found in fermented foods with many beneficial properties for the gut microbiota. Probiotics exhibit a variety of health beneficial properties for the gut as these microorganisms can prevent bowel diseases, improve the immune system, and prevent intestinal disorders’ effects on the digestive system.
Helping The Gut With Bugs
Research studies have found that probiotics play many significant roles in the gut microbiota composition while also inhibiting the colonization of pathogenic bacteria in the intestines. Since the gut microbiota contains a rich, diverse microbial ecosystem that can influence the health of the human body, so adding probiotics to combat the overflow of harmful bacteria infesting the intestinal walls can provide beneficial relief and help regulate the gut microbiota. The probiotics will also help the body build a healthy intestinal mucosa protective layer while enhancing theÂ immune system. Because of the close relationship between theÂ immune systemÂ and theÂ gut microbiota, probiotics are highly effective in improving immunity and regulating the gut microbiome.
Therapeutic Uses For Probiotics On Gut Disorders
Since theÂ gastrointestinal (GI) tractÂ is home to trillions of bacteria (both good and bad), there must be a balance between good and bad bacteria. These bacteria ensure that the gut microbiota is working correctly and prevent chronic gut disorders from inflicting on the intestinal wall barriers.Â Research studies have statedÂ that the perturbation of the bacterial microflora of the GI tract may play an essential role in the pathophysiology of GI disorders. Using probiotics as a part of a healthy diet can help dampen the effects of GI disorders by regulating the gut flora back to normal. Some of the therapeutic use that probiotics can help the gut microbiota when it comes to gut disorders include:
- Diarrhea (traveler’s, AAD, CDAD)
- Intestinal Permeability
Probiotics & IBD
Research studies have foundÂ that an altercation of the mucosal immune response to bacterial agents will lead to chronic intestinal inflammation that can characterize IBD (inflammatory bowel disease). Probiotics are safe for most individuals who have IBD and those with IBS (irritable bowel syndrome).Â Other research studies have statedÂ that when IBD individuals start to take probiotics can help normalize the gut barrier function and reduce the pro-inflammatory cytokines while lessening the disease. By taking probiotics, many individuals suffering from IBD will notice that their symptoms will diminish over time and that there will be positive outcomes seen at both low and high doses.
The gut system’s main job is to make sure that the food is being digested into nutrients and absorbed into the bloodstream to be transported throughout the entire body. When harmful pathogens enter the gut system, they can cause many digestive disorders that can upset the bacterial balance in the gut flora. When left untreated, it can develop into chronic gut diseases over time, causing the individual pain. Incorporating probiotics into a person’s diet can provide the beneficial results that a person needs. Probiotics can help replenish the healthy gut bacteria back to normal while dampening the effects of gut disorders from reoccurring in the intestinal tract. When individuals use probiotics as part of their diet, their gut will start to feel better and without pain.
Guandalini, Stefano, and Naire Sansotta. â€œProbiotics in the Treatment of Inflammatory Bowel Disease.â€ Advances in Experimental Medicine and Biology, U.S. National Library of Medicine, 2019, pubmed.ncbi.nlm.nih.gov/30632114/.
Hemarajata, Peera, and James Versalovic. â€œEffects of Probiotics on Gut Microbiota: Mechanisms of Intestinal Immunomodulation and Neuromodulation.â€ Therapeutic Advances in Gastroenterology, SAGE Publications, Jan. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3539293/.
Jonkers, Daisy, and Reinhold StockbrÃ¼gger. â€œProbiotics and Inflammatory Bowel Disease.â€ Journal of the Royal Society of Medicine, The Royal Society of Medicine, Apr. 2003, www.ncbi.nlm.nih.gov/pmc/articles/PMC539443/.
Shi, Lye Huey, et al. â€œBeneficial Properties of Probiotics.â€ Tropical Life Sciences Research, Penerbit Universiti Sains Malaysia, Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5031164/.
Verna, Elizabeth C, and Susan Lucak. â€œUse of Probiotics in Gastrointestinal Disorders: What to Recommend?â€ Therapeutic Advances in Gastroenterology, SAGE Publications, Sept. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC3002586/.
Wang, Xinzhou, et al. â€œProbiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity.â€ Molecules (Basel, Switzerland), MDPI, 8 Oct. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8512487/.
The information herein on "How Probiotics Dampen Gut Disorders | Part 2" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.
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