Randomized Controlled Trial

Randomized Controlled Trial or (RCT) can be performed by doctors, researchers, scientists, or health coaches. The design randomly assigns participants into an experimental group or a control group. As the study is conducted, the only expected difference between the control and experimental groups in a randomized controlled trial (RCT) is the outcome variable being studied.

In this type of study participants are divided by chance into separate groups that compare different treatments or other interventions. Using chance to divide people into groups means that the groups will be similar and that the effects of the treatments they receive can be compared more fairly. At the time of the trial, it is not known which treatment is best. Randomized Controlled Trails have help with many functional medicine supplements and other protocols.


Easier to blind/mask than from observational studies
Good randomization which washes out any population bias
Populations of participating individuals are clearly identified
Results can be analyzed with well known statistical tools


Does not reveal causation
Expensive in time and money
Loss to follow-up attributed to treatment
Volunteer biases: the population that participates may not be representative of the whole+

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